BIOGRAPHY - Page 10
Most of X-Force (both of them) went their separate ways, but Cable continued to pursue a pro-mutant tactical agenda. He dispatched Domino to chase a particular lead while following up on another with Hope, attending a weapons expo in Alexandria, Egypt. Then, everything went to hell. An arms dealer named Volga pilfered a bio-serum from another dimension that induced super-powers in others, but ultimately lead to a violently explosive meltdown in their system after 24 
hours. Volga improved upon the so-called "Volga Strain" and intended to kick off an arms race by using mutants as scapegoats. He infected a mutant anti-gun activist named Antjie Qoboza who was speaking at Alexandria before remotely triggering the meltdown in her system.
Cable had a precognitive flash and tried to stop it, but Volga's men shot him with the same serum. Cable attempted to isolate the bio-agent by severing his own arm with an ion blade, but the Volga Strain had already infected his metabolism, giving him a day to live at best. Worse, Hope copied his powers with her own and somehow created a psychic replica of the Volga Strain instability inside herself. Cable bodyslid away with Hope just as Qoboza erupted, destroying the arms depo and killing three thousands people. He found Fantomex and Marrow alive in the aftermath, both with their own problems or connection to Volga, and recruited them into X-Force.
Hope was placed in metabolic stasis while Doctor Nemesis went to work trying to recreate the Volga Strain itself, as well as the abstract copy Hope was hosting, in order to reverse the effects. Just as Volga intended, anti-mutant sentiment hit a record high after the Alexandria Incident. 
Unwilling to rest in stasis with Hope until Nemesis found a cure, Cable and Nemesis worked out a system. Cable's original body would remain frozen to prevent his Volga Strain countdown clock from running out. A cloned copy of Cable would operate in his place with full access to his memory engrams. Because the cloning process also copied the Volga Strain, however, each copy only had 24 hours to live. A special headband allowed each Cable to maintain a running "thoughtlog" of experiences, transferred to the next copy every day to maintain continuity in his goals and memories. Cable could not be copied from stasis, and so his original body was unfrozen briefly to make the new copies. The original Cable was still ticking closer to meltdown by about two minutes every day, and so X-Force's mission was on the clock. [X-Force (4th series) #5-6, 12]
With Hope and the Alexandria Incident as his guiding stars, Cable fully reorganized X-Force as a dirty tricks crew on behalf of the "mutant nation" as a whole. Psylocke, Marrow, Fantomex and Doctor Nemesis joined him in hunting down Volga. Cable's arm was still amputated from the Volga Strain and his mutant abilities were reduced to only a few seconds of precognitive foresight, 
but he persevered with a bionic arm, upgraded bodyslide tech and heavy ordinance. X-Force began operating out of the floating but decommissioned Helicarrier Pericles in the Pacific.
But... maybe it was the drive to save his daughter. Perhaps it was a degrading of moral judgement caused by the copying process, as Nemesis suggested. But Cable appeared increasingly, ethically compromised in his quest. He engaged in theft and assassinations in order to build intelligence. He compartmentalized missions and kept secrets from his allies, even about his own copying situation at first. He also exploited the services of Meme, the digital consciousness of a comatose mutant recovered from Volga's custody, unaware it was actually Hope psychically projecting through Meme's avatar due to the close proximity of their inert bodies back at base. Whatever got the job done. The team managed to confront Volga once and temporarily cripple his lab and operations, but the man himself escaped. The war continued. [X-Force (4th series) #1-6]
Cable's team soon began to fray at the edges. Fantomex suffered an existential crisis over his own self-worth compared to others, making him increasingly homicidal. Unknown to the others, he started killing Cable at the end of every day, after Nathan's thoughtlog had been uploaded to the next copy. Nathan and Psylocke also began a no-strings-attached sexual relationship, an oddly impersonal experience considering Nate wouldn't remember the encounters from one day to the next. As Cable occasionally suffered surprise deaths, it also created gaps in his thoughtlogs, causing him to forget about Domino's long-term mission into the Yellow Eye surveillance network. She was effectively burned and left in the cold where Mojo captured her and incorporated her into the Eye. [X-Force (4th series) #7]
X-Force eventually discovered the Yellow Eye independent of Domino's investigation, finding a worldwide watchdog set-up charging world governments for constant surveillance of mutant subjects. In another "ends justifying the means" arrangement, Cable and X-Force exploited the 
unique ability of the mutant Forgetmenot, exposing him to the Eye in order to track it back to its home base. [X-Force (4th series) #10] Cable's compartmentalizing increased during the Yellow Eye raid, as he sent one copy with the team as decoys while secretly sending a second Cable with Nemesis for a more covert infiltration. Much came to a head during the mission. Domino was rescued, but Nate's complete indifference to having forgot her made it a hollow victory for her. Hope's posturing as Meme was uncovered as well, and Fantomex finally turned on the team entirely. Having interfaced with Hope, he created a digital counterpart to her psychic copy of the Volga Strain and could now program himself with new super-powers on command. Still obsessed with proving himself the best, Fantomex decided to kill anyone who could potentially be considered better than him. [X-Force (4th series) #11-12]
X-Force hunted Fantomex around the world, as he seemingly attacked the international black-ops community. The final straw for Hope came, however, when she learned Fantomex was being lured to each target in advance by Cable. Taking advantage of Fantomex's compulsions, Cable was using him to weaken other nations on behalf of the "mutant nation." This was too much for Marrow, who put a spear through Cable's head, killing the only active copy. Hope managed to rally the remaining team, guiding Fantomex to the Pericles and copying his stable version of the Volga Strain to heal her body and mimic his advanced powers. As Hope and Nemesis shared their super-intelligence to find a final solution, Forgetmenot kicked the copying machine into high gear, unleashing an army of Cable clones to keep Fantomex busy.
Eventually, however, Fantomex was simply too powerful, and the original Cable had to be thawed out. Even with his psimitar to stabilize him, the Volga Strain countdown left him with only minutes by this point. Hope finally saved the day by creating a psychic bomb imprinted with the human imperfections of the team. By exposing Fantomex to this, his monomaniacal desire to be "the best" compelled him to purge all foreign impurities, which included the Volga Strain. Fantomex lost his extra powers, and Hope was able to copy the purging effect to cleanse herself and Cable of the Volga Strain once and for all.
The aftermath was bittersweet for Nathan, though. As he recuperated in the hospital, his body was fully restored. Even the eye and arm he had lost were regenerated by the tech on hand. 
However, his powers were at an all-time low, leaving him with only an unreliable precognitive insight. Hope had come to see the flaws in her father and her hero as well. Even the "diminished capacity" of the clones wasn't enough to make her completely forgive him for the amoral actions he took with X-Force. And so, she stole his team. Hope took command of X-Force and planned to keep them on the moral high ground while still protecting mutantkind, but Cable was "fired" until such a time as he realized how wrong he had been. [X-Force (4th series) #13-15]